{"id":1662,"date":"2020-11-04T13:43:02","date_gmt":"2020-11-04T13:43:02","guid":{"rendered":"https:\/\/tghd.flipside-staging.com\/?p=1662"},"modified":"2023-02-28T16:23:00","modified_gmt":"2023-02-28T16:23:00","slug":"could-gm-differences-in-people-with-ibd-lead-to-specific-treatments","status":"publish","type":"post","link":"https:\/\/www.theguthealthdoctor.com\/could-gm-differences-in-people-with-ibd-lead-to-specific-treatments","title":{"rendered":"Could GM differences in people with IBD lead to specific treatments?"},"content":{"rendered":"
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Altering our GM (gut microbiota) has been proposed as a treatment for Inflammatory Bowel Disease (IBD, as evidence suggests our gut microbiome plays an important role.<\/p>\n

But could differences in the gut microbiota (GM) of people with IBD lead to specific microbe-based treatments? A new review suggests maybe…but we’re not there yet!<\/p>\n

What did they do? <\/strong><\/h4>\n

Researchers pooled the results from 48 studies with over 2000 IBD patients, looking at differences in specific gut microbes between those with IBD vs healthy participants.<\/p>\n

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\"ibd.jpg\"<\/div>\n<\/figure>\n<\/div>\n<\/div>\n<\/div>\n
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What did they find?<\/strong><\/h4>\n
    \n
  • \n

    All the studies found differences in the GM of IBD patients and healthy controls, but these differences varied (exactly why I do NOT recommend commercial bacteria tests just yet).<\/p>\n<\/li>\n

  • \n

    75% of studies in Crohn’s showed a significant decrease in GM diversity, while for UC this was found in 29% of studies.<\/p>\n<\/li>\n

  • \n

    IBD patients had an increase of E.coli, possibly indicating previous infection or a change in the gut environment (this does NOT mean all E.coli are bad, some are actually probiotics!).<\/p>\n<\/li>\n

  • \n

    3 specific types of bacteria were decreased in people with Crohn’s, while 2 other specific types were decreased in those with UC (see image).<\/p>\n<\/li>\n

  • \n

    Both Crohn’s and UC had a reduction in a specific type of bacteria (called F prausnitzii), which may suggest a ‘protective’ role. That’s because it’s thought to be a main producer of a beneficial substance (a short-chain fatty acid called butyrate) that supports digestive health and may help with inflammation.<\/p>\n<\/li>\n<\/ul>\n

    BUT <\/strong>with many studies showing different results and using different methods, more large-scale studies need to be done before making concrete conclusions or personalised recommendations.<\/p>\n

    Ref: Pittayanon et al, Gastroenterology, 2020.<\/em><\/strong><\/p>\n<\/div>\n<\/div>\n","protected":false},"excerpt":{"rendered":"

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What did they…<\/p>\n","protected":false},"author":6,"featured_media":1021,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[49],"tags":[],"class_list":["post-1662","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-gut-issues"],"acf":[],"yoast_head":"\nCould GM differences in people with IBD lead to specific treatments? | The Gut Health Doctor<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.theguthealthdoctor.com\/could-gm-differences-in-people-with-ibd-lead-to-specific-treatments\" \/>\n<meta property=\"og:locale\" content=\"en_GB\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Could GM differences in people with IBD lead to specific treatments? | The Gut Health Doctor\" \/>\n<meta property=\"og:description\" content=\"Altering our GM (gut microbiota) has been proposed as a treatment for Inflammatory Bowel Disease (IBD, as evidence suggests our gut microbiome plays an important role. 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